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Summary
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Description |
English: Simplified schematic of the key pathways of paracetamol metabolism in the human body. The first step in conversion of paracetamol to NAPQI has been omitted for clarity. Set in Myriad Pro.
- Legend
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Pathways to non-toxic metabolites
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Pathway to toxic metabolites ( CYP-mediated)
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Detoxification pathway
- Abbreviations
- GlcA, glucuronic acid; GSH, glutathione; NAPQI, N-acetyl-p-benzoquinone imine.
Português: Esquema simplificado das principais vias de biotransformação do paracetamol em humanos. Para maior clareza, omitiu-se a primeira etapa da conversão do paracetamol à N-acetil-benzoquinoneimina. Diagrama composto em Myriad Pro.
- Legenda
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Vias de conversão a metabólitos atóxicos
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Via de conversão a metabólitos tóxicos (mediada pelo sistema P450)
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Via de detoxificação
- Abreviações
- GlcA, ácido glicurônico; GSH, glutationa; NAPQI, N-acetil-benzoquinoneimina.
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This vector image was created with Inkscape. |
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Date |
18 January 2009 |
Source |
Own work, after Henry, John (1995). “ Poisoning”, in Marshall, William Leonard. Clinical biochemistry: metabolic and clinical aspects, p. 666, Edinburgh: Churchill Livingstone, ISBN 9780443043413; and Hendrickson, Robert G.; Kenneth E. Bizovi (2006). “ Acetaminophen”, in Nelson, Lewis H.; Flomenbaum, Neal; Goldfrank, Lewis R. et al. Goldfrank's toxicologic emergencies, p. 525, New York: McGraw-Hill, ISBN 9780071437639. Both retrieved on January 18, 2009 through Google Book Search. |
Author |
Fvasconcellos ( talk · contribs) |
Permission ( Reusing this file) |
Public domainPublic domainfalsefalse |
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I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law.Public domainPublic domainfalsefalse
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SANGHARSH
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